Listening to prozac but hearing placebo

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Request (PDF) | Listening to Prozac | Posted 06/26/ Mean effect sizes for changes in depression were calculated for patients who had been randomly assigned to either antidepressant medication or placebo in 19 doubleblind clinical trials. As a proportion of the drug response, the placebo. Helping you find trustworthy answers | Latest evidence made easy.

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"Examination of pre–post effect sizes among depressed individuals assigned to no-treatment or wait-list control groups suggest that approximately one quarter of the drug response is due to the administration of an active medication, one half is a placebo effect, and the remaining quarter is due to other. Irving Kirsch is an expert in statistics and in clinical trial methodology. In The Emperor's New Drugs, he absolutely dismantles the case for antidepressants as a pharmacologically effective treatment.

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